Jake, Michael and Jaileigh building a tower.
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?
Michael
Source: http://4demarias.blogspot.com/2013/01/entertaining-jake.html
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Thursday, January 31, 2013
The DeMaria Family: Entertaining Jake
We have been trying to entertain Jake in quiet manners but it isn't really working. He is a hard man to keep down. As of now he has a black eye (from Jaileigh jumping on him), a scrape down his nose (from falling off the couch and hitting himself with his cast), and a hurt toe (don't know what happened), all to go with his broken arm. I keep telling him if he breaks his other arm he is going to have to stay on the couch allllllllll day long.
~House to Home~: Lets Get Creative!!!! An organized "Craft Room"
Challenge: This craft space needed to serve as storage and work space for a busy, creative family.
Goal:??The primary goal was to implement labeled storage that gave each item a home as well as organize it into zones:
?Books ? - Arts/Crafts ?- Paper ?- Wrapping - School/Office supplies ?- Sewing/Knitting?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?Before?
All items were removed from craft area and sorted by type. ?Once I knew how much of each item, I could create a space plan to?accommodate those items and maximize the storage space??
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? After
Zones were created by putting like items together to make it easier for the family to find the items they need as well as return them to their home. ?For example, the horizontal stacked trays became home to the different types of paper the client uses. ?The containers above the paper with smaller drawers are for small arts/craft items such a goggle eyes and other small craft items. ?The top shelf became home to all the family's arts/craft kits - such as beading kits, mosaic, etc.
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?Before
Client had already purchased storage containers, but they were not storing or organizing?efficiently.
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? After
Again, All items were removed from closet and sorted and?then?put into labeled storage?containers?based on size and type.
The shelf to the right was the perfect depth to store the clients movies so we actually moved them from a box the homeowner was storing. ?Now they family can see the videos they have and are more likely to watch them.
? ? ?? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? Before
? ? ? ? ? ? ? ? ? ? ? ? ? ? All books were taken off shelf and sorted by type and size.
? ?? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?After
After the books were sorted and organized by type and size ( ex: board books, chapter books, etc) they were returned to the shelf. ?We?utilized?the top shelf space for the client's?mailing and work supplies. ?This also kept these items out of reach from little hands.
On the floor, beneath the books, we created 2 storage bins labeled with each child's name. ?It creates a quick home for mom to put their school ?or art work in and she can go through ?it later and decide what she wants to keep. ?This will help keep the clutter off the counter space.
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?After
? ? ? ? ? ? ? ? ? ? ? ? ? ?? A home for school/office supplies
? ? ? ? ? ? ? ? ? ? ? ? ? ?
Source: http://housetohomedesign.blogspot.com/2013/01/lets-get-creative-organized-craft-room.html
"Hiring Our Heroes" job fair offers work for vets, military spouses
CARTERSVILLE, Ga. -- The U.S. Chamber of Commerce's National Chamber Foundation and The American Legion will host a job fair in Cartersville on Thursday, February 7.?
According to a spokeswoman for the job fair, "Hiring Our Heroes" is a way for veterans and military spouses to find work from over 20 employers. All levels of work experience are welcome to attend, and on hand will be representatives from America's biggest companies, as well as regional businesses.?
"Hiring Our Heroes," as reported, has helped around 14,000 people find jobs at over 400 nationwide events.?
The job fair will begin at 9:00 a.m. and last until noon. It will be held at the America Legion Post #42 at 1 Roosevelt Street.?
To register, contact Kim Morton at kmorton@uschamber.com?or call (202) 463-5725. Any vets who attend as a walk-in must provide their military ID.?
?
Source: http://dallas.11alive.com/news/155310-hiring-our-heroes-job-fair-offers-work-vets-military-spouses
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Wednesday, January 30, 2013
Intuit index: Small business employment grew in Texas and nationally in January
Map courtesty of Intuit Inc.
Small businesses across the country created 20,000 jobs this month, up 0.11 percent from a year earlier, according to data released today from the latest Intuit Payroll?s Small Business Index.
Texas small business employment grew 0.02 percent in January, the index showed.
Intuit tracks monthly employment, revenue and wage trends for small businesses ? those with fewer than 20 employees ? in 33 states. This month, eleven states showed job gains, two were flat and 20 showed declines. Utah and Nevada saw the largest increases.
U.S. small business employment continues to climb slowly after a slight dip from April through September, said Susan Woodward, the economist who helped create the Intuit indexes. However, the?19.9 million small business jobs is still below the pre-recession level of 21.2 million jobs in March 2007, she said.
Nationally, the average monthly pay for small-business workers fell a seasonally adjusted $6 in January after rising $13 in December. Monthly hours worked dipped slightly to 105.1 hours.
The nation can expect to see a decline in consumer spending as employees will take home less money given the return of the employee payroll tax to its previous level of 6.2 percent, Woodward said
Overall small business revenue dropped 0.4 percent in December ? down for 10th straight month according to the Intuit?s Small Business Revenue Index, which lags the employment index by one month. Construction was the only industry to see a revenue increase last month ? up 0.3 percent. Small business revenue is just now reaching pre-recession levels.
The employment index is based on data from 170,000 small business employers that use Intuit?s Online Payroll and QuickBooks Online Payroll. The revenue index is based on data from about 100,000 small businesses that use QuickBooks Online financial management product.
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Poor maintenance blamed for 2011 crash near Las Vegas
WASHINGTON (Reuters) - The National Transportation Safety Board said on Tuesday improper maintenance was the likely cause of a December 7, 2011, sightseeing helicopter crash near Las Vegas that killed the pilot and four passengers.
The board said its investigation of the crash of a Sundance Helicopters Eurocopter AS350 found inadequate maintenance, including degraded material, improper installation and inadequate inspections.
"This investigation is a potent reminder that what happens in the maintenance hangar is just as important for safety as what happens in the air," NTSB Chairman Deborah Hersman said in a statement.
The helicopter, operating as a "Twilight City Tour" air tour, crashed in mountainous terrain about 14 miles east of Las Vegas on December 7, 2011, less than 10 minutes after it left Las Vegas McCarran International Airport en route to Hoover Dam.
The NTSB said the accident occurred after one critical flight control unit separated from another, which sent the helicopter first higher, then into a sharp descent at a rate of at least 2,500 feet per minute.
The NTSB found that the crash was the result of Sundance Helicopters' improper reuse of a degraded self-locking nut, and the improper or nonuse of a split pin to secure the degraded nut, in addition to an inadequate post-maintenance inspection.
The investigation found that both the mechanic and the post-maintenance inspector were fatigued and did not have clearly delineated steps to follow on a "work card" or "checklist."
As a result of the crash, the NTSB said it made, reiterated and reclassified recommendations to the Federal Aviation Administration about the need for improved maintenance documentation.
"One of the critical lines of defense to help prevent tragedies like this crash is improved maintenance documentation through clear work cards, or checklists," Hersman said. "Checklists are not rocket science, but they can have astronomical benefits."
A synopsis of the NTSB report, including the probable cause, findings, and a complete list of the safety recommendations, is available at www.ntsb.gov/news/events/2013/las_vegas_nv/index.html
(Reporting by Andrea Shalal-Esa; Editing by Jackie Frank)
Prehistoric humans not wiped out by comet, says researchers
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Public release date: 30-Jan-2013[ | E-mail |
Share ] Contact: Tanya Gubbay
tanya.gubbay@rhul.ac.uk
Royal Holloway, University of London
Comet explosions did not end the prehistoric human culture, known as Clovis, in North America 13,000 years ago, according to research published in the journal Geophysical Monograph Series.
Researchers from Royal Holloway university, together with Sandia National Laboratories and 13 other universities across the United States and Europe, have found evidence which rebuts the belief that a large impact or airburst caused a significant and abrupt change to the Earth's climate and terminated the Clovis culture. They argue that other explanations must be found for the apparent disappearance.
Clovis is the name archaeologists have given to the earliest well-established human culture in the North American continent. It is named after the town in New Mexico, where distinct stone tools were found in the 1920s and 1930s.
Researchers argue that no appropriately sized impact craters from that time period have been discovered, and no shocked material or any other features of impact have been found in sediments. They also found that samples presented in support of the impact hypothesis were contaminated with modern material and that no physics model can support the theory.
"The theory has reached zombie status," said Professor Andrew Scott from the Department of Earth Sciences at Royal Holloway. "Whenever we are able to show flaws and think it is dead, it reappears with new, equally unsatisfactory, arguments.
"Hopefully new versions of the theory will be more carefully examined before they are published".
###
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 30-Jan-2013[ | E-mail |
Share ] Contact: Tanya Gubbay
tanya.gubbay@rhul.ac.uk
Royal Holloway, University of London
Comet explosions did not end the prehistoric human culture, known as Clovis, in North America 13,000 years ago, according to research published in the journal Geophysical Monograph Series.
Researchers from Royal Holloway university, together with Sandia National Laboratories and 13 other universities across the United States and Europe, have found evidence which rebuts the belief that a large impact or airburst caused a significant and abrupt change to the Earth's climate and terminated the Clovis culture. They argue that other explanations must be found for the apparent disappearance.
Clovis is the name archaeologists have given to the earliest well-established human culture in the North American continent. It is named after the town in New Mexico, where distinct stone tools were found in the 1920s and 1930s.
Researchers argue that no appropriately sized impact craters from that time period have been discovered, and no shocked material or any other features of impact have been found in sediments. They also found that samples presented in support of the impact hypothesis were contaminated with modern material and that no physics model can support the theory.
"The theory has reached zombie status," said Professor Andrew Scott from the Department of Earth Sciences at Royal Holloway. "Whenever we are able to show flaws and think it is dead, it reappears with new, equally unsatisfactory, arguments.
"Hopefully new versions of the theory will be more carefully examined before they are published".
###
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-01/rhuo-phn013013.php
PFT: Urlacher has to take pay cut to stay with Bears
APThe bounty case essentially is over, but bits and pieces of evidence continue to surface.
More than a few bits and pieces have come from the disclosure of a significant portion of the appeal hearing testimony from former Saints interim head coach and current linebackers coach Joe Vitt.
Among many other things, Vitt?s testimony before former Commissioner Paul Tagliabue sheds light on some of the contentious aspects of the relationship between the league office and the organization.? Vitt says that, at one point, Saints owner Tom Benson told NFL V.P. of security Jeff Miller to leave the premises.
?Jeff Miller took a plane ride from New York down to New Orleans, and the way he talked to our owner, what he said to our owner made me want to throw up, to the point where Mr. Benson kicked him off the property and didn?t let him back on the property,? Vitt said, via the New Orleans Times-Picayune.
?This almost killed our owner.? Our owner has done nothing but be a great owner in the National Football League the whole time he?s been in the league. . . .? And now this guy takes a plane ride down and throws some documents in front of our owner?s face, and our owner has got to kick him out of the building?? That?s what we?re dealing with.? That?s fine.?
Vitt also explained that, even though notes generated by former Saints assistant Mike Cerullo indicated that Vitt had offered $5,000 to the alleged bounty on former Vikings quarterback Brett Favre, Miller didn?t believe it happened.
?The investigators, Jeff Miller in particular, acknowledged that I did not give any money to a bounty because he said to me, you know, we heard that your wife is so cheap that you have a hard time getting lunch money every day,? Vitt said.? ?That was his comment to me.? And I said, well, your wife must have a pretty good sense of humor, too, with the clothes you?re wearing right now.?
Vitt also had some strong comments for Cerullo.
?Mike Cerullo is a liar,? Vitt said. ?We?ll get some notes here from Mr. Cerullo. I?ll say this to you, Commissioner, and anybody that?s interested. I?m taking Mike Cerullo to court.? I?m going to sue his ass for the things he said about me, the things he said about this football team.? He?s going to be held accountable for everything he said. I make this offer again.? If we want me to take a lie detector test this afternoon, I will do so.? Or if you want me to do it tomorrow morning or tomorrow afternoon, I will do so. Mike Cerullo is a liar.? A liar.?
Vitt also talked at length regarding coach Sean Payton?s decision after the 2011 season to part ways with defensive coordinator Gregg Williams.? Payton began to sour on Williams after the head coach caught Williams texting draft picks to the media during the 2011 selection process.
?I would say the final straw was the last two weeks of the season,? Vitt said.? ?Gregg kept coming to Sean every day and wanted his contract extension and wanted his extension done.? And Sean said, well, we?ll talk about it at the end of the season, well knowing what direction Sean was going in.? And the last week of the season, it?s all in the papers, you know, Gregg has gone to St. Louis, it?s his best friend Jeff Fisher, you know, ba-boom, ba-boom, ba-boom, trying to squeeze Sean, trying to squeeze Mickey to get his contract.? And the day after the playoff game that we lost against San Francisco, he went into Sean?s office and says I need to know right now, I need my contract, I?ve got to let Jeff know what I?m doing.? And Sean said, you?re not going to get a contract here.? I think it?s best go to St. Louis with your friend Jeff. And that was it. . . .? It didn?t end pretty. It didn?t end nice.?
There isn?t much nice or pretty about Vitt?s testimony, but it?s compelling and interesting and he has the kind of passion that typically is exhibited by a guy who has been accused of things he didn?t do.
Lilly says generic competition hurts profit, sales
(Reuters) - Eli Lilly and Co
The U.S. drugmaker earned $827 million, or 74 cents per share, down from $858 million, or 77 cents per share, a year earlier.
Excluding special items such as asset impairments and restructuring, Lilly earned 85 cents per share. Analysts, on average, expected 78 cents per share.
Revenue dropped by about 1 percent to $5.96 billion, but were above Wall Street expectations of $5.81 billion.
Zyprexa sales slid 49 percent to $385 million from $750 million a year earlier. The company said the sharp drop was partly offset by gains in sales of other drugs and its animal health products.
Lilly forecast that earning would increase this year by 13 percent to 17 percent to $3.82 to $3.97 per share, excluding special items, due to cost controls. Profit will benefit by 7 cents per share due to a research and development tax credit that was delayed until this year due to the late signing of federal legislation.
It predicted sales will be flat to a bit higher this year, in a range of $22.6 billion to $23.4 billion, despite expected generic competition in December for its $5-billion-a-year antidepressant Cymbalta.
Lilly has been battered over the past year by generic forms of Zyprexa. Besides the looming threat from Cymbalta generics, it is girding for copycat forms of its $1 billion-a-year Evista osteoporosis drug that are due to arrive in early 2014.
Cymbalta had sales of $1.42 billion in the fourth quarter, up 20 percent from a year earlier, and a total of $4.99 billion in 2012.
The company hopes to cushion the blow from generics with approvals of some of its 13 experimental drugs now in late-stage trials.
(Reporting by Caroline Humer and Ransdell Pierson; Editing by Lisa Von Ahn and Jeffrey Benkoe)
Source: http://news.yahoo.com/lilly-fourth-quarter-profit-fall-generics-hurt-sales-114650939--finance.html
Tuesday, January 29, 2013
two checking accounts? : Personal Finance
I used 2 checking accounts (bills and other) before starting YNAB. It's probably the only reason I still own my house and didn't lose a car or anything during some time when I was not paying attention to my finances (except my credit limits). I continued to keep the two separate accounts for the first two years I used YNAB, because I didn't trust myself not to spend my 'bills' money on other stuff. I also, during my first year of ynab, didn't use credit cards at all, so I used that 'other' account with a debit card (no debit card for the bills account) for all other spending, besides bills.
YNAB is more complex with more accounts. I had one master category for my bills, and I kept the balance in that account around that of the master. However, this does require extra work, as YNAB doesn't care where the money lives for any particular category. Since I had things very well compartmentalized, it wasn't too bad. When it really gets difficult is if you have one expense that you sometimes pay from one account and sometimes from the other. Or if one is a savings account that you want to match a category to, but you can't spend from the account because it's savings. Etc.
Pros without YNAB, you can look at your bank balance and know what you can spend on the expenses you designate as coming from that account (in aggregate).
Cons without YNAB, can't think of any.
Cons with YNAB, it adds a layer of complexity. And if you're just learning how YNAB works, it can be a bit much for some to make it work like this
Pros with YNAB, can't think of any (except an extra layer of protection...which isn't necessary if you spend according to category limits as ynab is designed to do).
One thing I DID switch when I moved to YNAB, even though I kept the extra account. I used to have the exact amount for my bills go to my bills account and the rest went to my 'spending' account. So...I spent it. When I started YNAB and I wanted the extra money to be sent off to the credit card as an extra/snowball amount at the end of the month if I had anything left, I started putting a little less that when I thought I'd spend into the spending account and left the bills account on the heavy side. Sometimes I had to transfer more over, but I was often able to send more at the end of the month to the evil credit cards.
I did sweat the transferring a bit. Now I know that I was probably making myself overly crazy by doing that and that as long as I was spending according to category balances, it would have worked out just the same if I hadn't kept the spending account as lean as I did. But it worked.
You mentioned a reason that you'd open an account at the one bank because it's more convenient, but you don't say why you wouldn't be considering just moving over to the more convenient bank entirely. If you don't need two accounts, don't keep the old one. (Or if you don't get charged fees, just keep it but don't use it...or keep enough there to avoid vees, etc.)
Malisa
For live classes and recorded classes: http://www.youneedabudget.com/support/training-and-education
For help files and short tutorial videos: http://www.youneedabudget.com/support
(copy and paste into your browser)
Source: http://www.youneedabudget.com/forum/personal-finance-f9/two-checking-accounts-t20053.html
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Climate change impacts to U.S. coasts threaten public health, safety and economy, report finds
Jan. 28, 2013 ? According to a new technical report, the effects of climate change will continue to threaten the health and vitality of U.S. coastal communities' social, economic and natural systems.
The report, Coastal Impacts, Adaptation, and Vulnerabilities: a technical input to the 2013 National Climate Assessment, authored by leading scientists and experts, emphasizes the need for increased coordination and planning to ensure U.S. coastal communities are resilient against the effects of climate change.
The recently released report examines and describes climate change impacts on coastal ecosystems and human economies and communities, as well as the kinds of scientific data, planning tools and resources that coastal communities and resource managers need to help them adapt to these changes.
"Sandy showed us that coastal states and communities need effective strategies, tools and resources to conserve, protect, and restore coastal habitats and economies at risk from current environmental stresses and a changing climate," said Margaret A. Davidson of NOAA's Office of Ocean and Coastal Resource Management and co-lead author of the report. "Easing the existing pressures on coastal environments to improve their resiliency is an essential method of coping with the adverse effects of climate change."
A key finding in the report is that all U.S. coasts are highly vulnerable to the effects of climate change such as sea-level rise, erosion, storms and flooding, especially in the more populated low-lying parts of the U.S. coast along the Gulf of Mexico, Mid-Atlantic, northern Alaska, Hawaii, and island territories. Another finding indicated the financial risks associated with both private and public hazard insurance are expected to increase dramatically.
"An increase in the intensity of extreme weather events such as storms like Sandy and Katrina, coupled with sea-level rise and the effects of increased human development along the coasts, could affect the sustainability of many existing coastal communities and natural resources," said Virginia Burkett of the U.S. Geological Survey and co-lead author of the report.
The authors also emphasized that storm surge flooding and sea-level rise pose significant threats to public and private infrastructure that provides energy, sewage treatment, clean water and transportation of people and goods. These factors increase threats to public health, safety, and employment in the coastal zone.
The report's authors noted that the population of the coastal watershed counties of the U.S. and territories, including the Great Lakes, makes up more than 50 percent of the nation's population and contributed more than $8.3 trillion to the 2011 U.S. economy but depend on healthy coastal landforms, water resources, estuaries and other natural resources to sustain them. Climate changes, combined with human development activities, reduce the ability of coasts to provide numerous benefits, including food, clean water, jobs, recreation and protection of communities against storms.
Seventy-nine federal, academic and other scientists, including the lead authors from the NOAA and USGS, authored the report which is being used as a technical input to the third National Climate Assessment -- an interagency report produced for Congress once every four years to summarize the science and impacts of climate change on the United States.
Other key findings of the report include:
- Expected public health impacts include a decline in seafood quality, shifts in disease patterns and increases in rates of heat-related morbidity.
- Changes in the location and the time of year when storms form can lead to large changes in where storms land and the impacts of storms. Any sea-level rise is virtually certain to exacerbate storm-surge and flooding related hazards.
- Because of changes in the hydrological cycle due to warming, precipitation events (rain, snow) will likely be heavier. Combined with sea-level rise and storm surge, this will increase flooding severity in some coastal areas, particularly in the Northeast.
- Temperature is primarily driving environmental change in the Alaskan coastal zone. Sea ice and permafrost make northern regions particularly susceptible to temperature change. For example, an increase of two degrees Celsius during the summer could basically transform much of Alaska from frozen to unfrozen, with extensive implications.
- As the physical environment changes, the range of a particular ecosystem will expand, contract or migrate in response. The combined influence of many stresses can cause unexpected ecological changes if species, populations or ecosystems are pushed beyond a tipping point.
- Although adaptation planning activities in the coastal zone are increasing, they generally occur in an ad-hoc manner and are slow to be implemented. Efficiency of adaptation can be improved through more accurate and timely scientific information, tools, and resources, and by integrating adaptation plans into overall land use planning as well as ocean and coastal management.
- An integrated scientific program will reduce uncertainty about the best ways coastal communities can to respond to sea-level rise and other kinds of coastal change. This, in turn, will allow communities to better assess their vulnerability and to identify and implement appropriate adaptation and preparedness options.
This report is available online.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/LJ4zZMA7j_g/130128143010.htm
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Apple releases iOS 6.1, giving Siri the power to buy movie tickets
40 min.
Apple has released a software update?? iOS 6.1 ? which gives you the ability to purchase movie tickets through?Fandango using Siri, supports LTE?capabilities?for a bunch of carriers around the world?and adds the ability to download individual songs from iCloud.
You can find a complete list of the newly supported LTE-capable carriers on Apple's website.?(There's now support for LTE connectivity for 36 additional iPhone carriers and 23 additional iPad carriers around the world.)?
iOS 6.1 is available is compatible with the?iPhone 5, iPhone 4S, iPhone 4, iPhone 3GS, third- and fourth-generation?iPad, iPad Mini, iPad 2,?and fourth- and fifth-generation?iPod Touch. You can snag it by?connecting your device to iTunes and hitting the "check for updates" button. (Alternatively, head into your gadget's "Settings" menu, select the "General" tab, and tap the "Software Updates" option to download the update over?the air.)
Want more tech news?or interesting?links? You'll get plenty of both if you keep up with Rosa Golijan, the writer of this post, by following her on?Twitter, subscribing to her?Facebook?posts,?or circling her?on?Google+.
Ultrasound Breast Cancer Imaging Invented At Karmanos Closer To ...
DETROIT ? SoftVue, the whole breast ultrasound imaging device created by two scientists from the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine, is currently undergoing review by the U.S. Food and Drug Administration for market clearance.
It?s anticipated that this first application clearance could come this spring, with several other FDA submissions to follow over the next couple of years. This promising imaging tool has the potential to aid in detecting breast cancer earlier, especially in women with dense breasts.
Peter Littrup and Neb Duric of the Karmanos Cancer Institute and Wayne State University School of Medicine, and their team have been working to perfect the SoftVue technology for more than a decade.
The Karmanos Cancer Institute spun off a company in 2009 called Delphinus Medical Technologies to help secure funding to bring this device closer to commercialization. Since then, Delphinus has grown to 19 employees, many of whom are engineers, and plans are underway to gradually increase the sales staff once the first FDA market clearance is obtained.
Said Gerold Bepler, M.D., president and CEO of the Barbara Ann Karmanos Cancer Institute: ?Information obtained from this new SoftVue system will continue the next round of clinical research for use in diagnostic breast imaging. SoftVue is another example of the exceptional cancer research and innovative technology created right here at the Karmanos Cancer Institute in Detroit, and built in Michigan.?
More than $32 million in funding, including venture capital and other grants, helped turn SoftVue?s technology into a commercial product, pending FDA clearance to market. The first round of venture capital funding included Michigan companies Arboretum Ventures, Altarum Institute, Beringea, LLC?s InvestMichigan Growth Capital Fund and North Coast Technology Investors. Other funding, past and present, was received from several private donors along with grants from the National Institutes of Health, the Susan G. Komen Breast Cancer Foundation and the Michigan Economic Development Corp. Currently, the Karmanos Cancer Institute has the only commercial-grade SoftVue system in the world.
SoftVue uses ultrasound waves, rather than X-rays, to create its images. Karmanos officials say ultrasound waves have the potential to detect early stages of breast cancer, even in women with dense breast tissue, where early stage cancers are often not picked up by mammography.
The interaction of sound waves with cancerous tissue yields a unique signature that can be measured using the SoftVue technology. The SoftVue system collects information not often detected by conventional ultrasound imaging, resulting in a more accurate and complete image of the tissue characteristics.
The SoftVue exam takes about a minute, produces images for the radiologist in less than 15 minutes, does not involve the radiation or compression used in mammography, and is a fraction of the cost of breast magnetic resonance imaging.
With SoftVue, the breast is submerged in warm water and an ultrasound transducer ring surrounds the breast without touching it. The SoftVue system transmits and receives ultrasound signals around the entire breast that allow it to capture detailed, three-dimensional images.
The system is able to perform repeated imaging, a necessary tool for biopsy, monitoring and treatment assessment.
SoftVue?s detailed images aid the radiologist in making an accurate breast cancer diagnosis. It?s believed that SoftVue could help reduce the number of false positives that can occur with mammography and thereby reduce unnecessary biopsies.
Once market clearance is received for the first FDA submission, other SoftVue systems will be produced for other medical centers that will take part in clinical studies needed to secure further FDA approvals for SoftVue. Up to now, SoftVue studies were only for diagnostic purposes, showing the quality and safety of this technology compared to other ultrasound breast cancer imaging devices.
The company plans to carry out clinical trials involving approximately 15,000 to 20,000 subjects to support an FDA Pre-Market Approval Application, which, once approved, will give Delphinus the green light to sell SoftVue for breast cancer screening in the United States. William Greenway, Delphinus? CEO, anticipates that could take until 2015, depending on the number of people participating in the clinical studies at various medical centers, as well as funding to manufacture the systems.
?Once we secure this first FDA clearance, we?ll receive signed commitments from other health centers that have expressed interest in SoftVue,? Greenway said. ?The approximate cost for the SoftVue machine is $400,000, comparable to mammography. We anticipate that we?ll need another $15 to $17 million in venture capital to carry out the trials and produce the machines, which will be manufactured in Michigan.?
Mammography is still the gold standard in breast cancer screening; however, for hospitals and medical centers such as the Karmanos Cancer Institute where SoftVue will be available, SoftVue will serve as a follow-up to breast cancer screening upon initial FDA market clearance.
Currently, SoftVue is available at the Karmanos Cancer Institute and Karmanos patients may sign up to be part of the ongoing clinical studies. Once the first FDA clearance is secured, additional SoftVue systems will be produced and placed in other medical centers interested in this technology.
For more information on SoftVue technology contact Delphinus Medical Technologies at (734) 233-3088. For patients interested in participating in SoftVue?s clinical studies for breast cancer screening, call the Karmanos Cancer Institute at 1-800-KARMANOS (1-800-527-6266.)
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2 science projects win up to $1.3 billion each
FILE - In this May 9, 2011 file picture people use a infrared-DIC microscopy to do multi-neuron patch-clamp recording in the Blue Brain team and the Human Brain Project (HBP) laboratory of the Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. The Blue Brain team has come together with 12 other European and international partners to propose the Human Brain Project (HBP), a candidate for funding under the EU's FET Flagship program. The Blue Brain Project is an attempt to create a synthetic brain by reverse-engineering the mammalian brain down to the molecular level. (AP Photo/Keystone/Laurent Gillieron)
FILE - In this May 9, 2011 file picture people use a infrared-DIC microscopy to do multi-neuron patch-clamp recording in the Blue Brain team and the Human Brain Project (HBP) laboratory of the Ecole Polytechnique Federale de Lausanne (EPFL), in Lausanne, Switzerland. The Blue Brain team has come together with 12 other European and international partners to propose the Human Brain Project (HBP), a candidate for funding under the EU's FET Flagship program. The Blue Brain Project is an attempt to create a synthetic brain by reverse-engineering the mammalian brain down to the molecular level. (AP Photo/Keystone/Laurent Gillieron)
BRUSSELS (AP) ? Two European science projects ? one to map the intricacies of the human brain, the other to explore the extraordinary carbon-based material graphene ? won an EU technology contest Monday, getting up to ?1 billion ($1.34 billion) each over the next decade.
The projects were selected from 26 proposals.
"European's position as a knowledge superpower depends on thinking the unthinkable and exploiting the best ideas," European Commission Vice President Neelie Kroes said in a statement. "This multi-billion competition rewards home-grown scientific breakthroughs and shows that when we are ambitious we can develop the best research in Europe."
The Human Brain Project will use supercomputers 1,000 times more powerful than those today to create the most detailed model ever of the human brain. Then the project plans to simulate the effects of drugs and treatments on the brain, for a better understanding of neurological diseases and related ailments.
In addition, the increased knowledge about how the brain works ? and how it manages billions of processing units and trillions of synapses while consuming no more power than a light bulb ?may lead to "a paradigm shift for computing," the European Commission, the European Union's executive branch, said in a statement.
"The economic and industrial impact of such a shift is potentially enormous," the Commission said.
The leader of the project, Henry Markram, a professor of neuroscience at the Ecole Polytechnique Federale of Lausanne in Switzerland, said earlier this month that it could not be undertaken without this kind of funding.
"The pharmaceutical industry won't do this, computing companies won't do this ? there's too much fundamental science," Markram said. "This is one project which absolutely needs public funding."
The other project will investigate the possible uses of graphene, the thinnest known material, which conducts electricity far better than copper, is perhaps 300 times stronger than steel and has unique optical properties. A sheet of it is one atom thick; scientists call it the first known two-dimensional material.
Important future uses include the development of fast, flexible and strong consumer electronics, bendable personal communication devises, lighter airplanes, cars that use less energy and artificial retinas.
The project will be led by professor Jari Kinaret of the Chalmers University of Technology in Goteborg, Sweden.
"The story of graphene shows there is still wonder in science," Kroes said Monday at a news conference. "It's like a miracle."
In 2010, the Nobel Prize in Physics was awarded to two scientists at the University of Manchester in Britain "for groundbreaking experiments regarding the two-dimensional material graphene."
"So, you've heard of Silicon Valley," Kroes said. "'Where in Europe wants to be known as 'Graphene Valley?' That's the billion-euro question I am putting to you today."
Each of the projects will initially receive ?54 million ($73 million) from the European Union's research budget, an amount that will be matched by national governments and other sources. Further funding will depend on whether they reach certain milestones within the first 30 months, but over a decade it could total ?1 billion ($1.34 million) each.
In this age of government austerity, the Commission promised to monitor the projects carefully so they continue to "be an efficient use of taxpayers' money."
The winners were selected by a panel of 25 experts, including professors, scientists and Nobel winners. The two other projects that made the finals were one to develop digital guardian angels to keep people from harm and a massive data-crunching machine to simulate social, economic and technological change on Earth.
___
Don Melvin can be reached at http://twitter.com/Don_Melvin .
Associated PressHospital that trashed kidney resumes transplants
TOLEDO, Ohio (AP) ? An Ohio hospital where a nurse accidentally threw out a viable kidney has resumed its kidney transplant program.
The University Toledo Medical Center had voluntarily suspended the transplant program after the Aug. 10 accident. After an investigation and policy changes, the hospital announced last month it was ready to resume the living-donor program.
Hospital spokesman Jon Strunk told The (Toledo) Blade (http://bit.ly/XakoLw ) that the first surgery took place Thursday. He declined to provide patient information.
A report by a surgeon hired by the hospital to review its transplant program called it "baffling" that the nurse would accidentally put the viable kidney with medical waste. But he found no problems with the systems that would have indicated the hospital was at risk for such a mistake.
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Information from: The Blade, http://www.toledoblade.com/
Source: http://news.yahoo.com/hospital-trashed-kidney-resumes-transplants-112908552.html
Sampling from VLC - Renoise Forums
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?
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Posted Yesterday, 02:38 AM
A quick question just came to mind, as this seems a bit easier on linux (for a change) than on windows: how can you record a sample from say a movie, playing in e.g. vlc, into renoise? I used to just Convert the whole movie to mp3 and look for the good parts, but that annoying and tedious and takes all the fun out of the sampling. In linux I can just reroute some cables in JACK and I can straight hit record from renoise!
Anybody know of a good tool for this? VLC doesn't play through ASIO4All does it?
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#2 
?
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Posted Yesterday, 02:47 AM
Cas, on 27 January 2013 - 02:38 AM, said:
A quick question just came to mind, as this seems a bit easier on linux (for a change) than on windows: how can you record a sample from say a movie, playing in e.g. vlc, into renoise? I used to just Convert the whole movie to mp3 and look for the good parts, but that annoying and tedious and takes all the fun out of the sampling. In linux I can just reroute some cables in JACK and I can straight hit record from renoise!
Anybody know of a good tool for this? VLC doesn't play through ASIO4All does it?
Virtual Audio Cable is one way. Another way depends if your soundcard driver has the function built in, something like "What U Hear" or "Loopback" are features available to do just that kind of thing.
Also, depending on the video format, you can actually load the video in to renoise in as a sample.
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#3 ?
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Posted Yesterday, 10:10 AM
What I do is use my consumer-level soundcard as my default sound card in windows, and have the output routed physically into my professional audio card. I have it always monitoring, so I can always hear my regular computer sounds, while also being able to use my pro audio card for making music and sampling sounds from my PC.
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#4 ?
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Posted Yesterday, 12:31 PM
A lot of consumer level soundcards, such as the onboard chipsets on motherboards, have a Record What You Hear type feature. This is what I've usually used. Not perfect but acceptable and easier, faster and more convenient than converting the whole file (and unless you are ripping the audio stream, rather than converting, possibly higher quality too.)I would generally try and avoid going out of an onboard chipset and into your main audio interface. This is likely to give the lowest quality results out of all possible methods. Although some onboard chipsets are too bad these days so depending on your setup you might get perfectly usable results (as I assume Veggies must do.)
I don't think VLC has ASIO. There is an ASIO plugin for Winamp though.
http://www.winamp.co...t-plugin/156466
Or for Foobar: http://www.foobar200...ew/foo_out_asio
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#5 ?
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Posted Yesterday, 12:42 PM
Cas, on 27 January 2013 - 02:38 AM, said:
A quick question just came to mind, as this seems a bit easier on linux (for a change) than on windows: how can you record a sample from say a movie, playing in e.g. vlc, into renoise? I used to just Convert the whole movie to mp3 and look for the good parts, but that annoying and tedious and takes all the fun out of the sampling. In linux I can just reroute some cables in JACK and I can straight hit record from renoise!
Anybody know of a good tool for this? VLC doesn't play through ASIO4All does it?
Jack also works for Windows, but you need a video player capable of using Jack and you can only use Jack for the 32-bit version of Renoise since the 64-bit version somehow doesn't seem to be able connect.
Reaper can play video files so you might as well be able to link audio from Reaper to Renoise using Jack. But Reaper also has ReaRoute so you might as well slave Renoise to Reaper using ReaRoute and then toy with your movies.
cpu Intel Core2 Quad CPUQ6600 @2.40GHz
chipset nVidia nForce 4 SLI x16 -> Driver rev:5.1.2600.445 (management 4.4.5.0)
mem 8 Gb 800Mhz
os Win 7 64-bit SP1, DirectX 11
audio ESI ESP1010e - > Driver rev:2.0.1.0
video nVidia Geforce GTX580 - > Driver rev:306.23
Renoise Official Manual
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Posted Yesterday, 01:59 PM
isn't there just a "dump audio output to file" dummy audio driver?
with mplayer i can just do "mplayer -vo null -ao pcm <videofile>" and i get an audiodump.wav file.
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#7 ?
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Posted Yesterday, 02:07 PM
visinin, on 27 January 2013 - 01:59 PM, said:
isn't there just a "dump audio output to file" dummy audio driver?
with mplayer i can just do "mplayer -vo null -ao pcm <videofile>" and i get an audiodump.wav file.
He already said currently he rips the entire soundtrack and then cuts out the bit and that's what he wants to avoid in future. Is that not what this method would do? I know Winamp has a similar feature but it can only route to one output from what I remember (but I generally use an antiquated version as 2.x was always better for Shoutcast streaming than 5.x historically.) Plus I know I have run into issues with playback speed using this, think you need to make sure the soundcard samplerate is set the same as the audio you are ripping.
If you note down times of the wanted sample it might still be a slight advance on ripping the entire soundtrack and editing after though...
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Posted Yesterday, 03:00 PM
kazakore, on 27 January 2013 - 02:07 PM, said:
If you note down times of the wanted sample it might still be a slight advance on ripping the entire soundtrack and editing after though...
Yeah that'll probably be the windows workflow.. trying the virtual cable program linked by Jenoki but it definitely doesn't seem as straightforward a setup as jackcontrol is.
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Source: http://forum.renoise.com/index.php?/topic/37126-sampling-from-vlc/
Monday, January 28, 2013
Maine gas prices up almost 3 cents per gallon
AUGUSTA, Maine (AP) -- The cost of a gallon of gas in Maine has jumped nearly three cents in the past week.
Price-monitoring website MaineGasPrices.com reports Monday that the average retail cost of a gallon of gas rose to $3.55. The price is based on a survey of more than 1,200 gas stations in the state.
Even though the national average rose more than four cents in the same time span, the average price in Maine remains 24 cents higher per gallon.
Current prices in Maine are just about the same as they were a year ago.
A company analyst says prices are rising because this is traditionally refinery maintenance season, when production drops.
Source: http://news.yahoo.com/maine-gas-prices-almost-3-160929839.html
Join the WWE Royal Rumble 2013 Live Chat!
Join WWE Hall of Famer Howard Finkel and the WWE.com team for live coverage of WWE Royal Rumble 2013, including live results and commentary on the 30-man Royal Rumble Match! The Live Chat with The Fink begins at 7 PM ET.
Will "The People's Champion" dethrone the champion who abandoned the WWE Universe, CM Punk? Can Alberto Del Rio hold on to his newly won World Heavyweight Championship in a Last Man Standing rematch against Big Show? Which Superstar will win the Royal Rumble Match and leave Phoenix with a guaranteed World Title Match at WrestleMania 29? Find out tonight when the Royal Rumble returns live to pay-per-view at 8 ET/5 PT! (HOW TO WATCH)
WWE Championship Match
CM Punk (c) vs. The Rock (PREVIEW)
30-Superstar Royal Rumble Match (PREVIEW | ROYAL RUMBLE MATCH: BY THE NUMBERS)
World Heavyweight Championship Last Man Standing Match
Alberto Del Rio (c) vs. Big Show (PREVIEW)
WWE Tag Team Championship Match
Team Hell No (c) vs. Team Rhodes Scholars (PREVIEW)
United States Championship Match (Pre-Show)
Antonio Cesaro (c) vs. The Miz (PREVIEW)
?
Source: http://www.wwe.com/shows/royalrumble/2013/royal-rumble-live-chat
American Idol Official leads iOS Apps of the Week
Headling this week's best iOS apps is American Idol Official, a mobile offering that celebrates the televised singing contest, now in its twelfth year. If you?re not into reality TV, we also have solid apps for the X Games, weird facts, grammar, and mathematical calculations.
While it?s hardly my favorite show, it?s hard to dismiss the cultural impact of American Idol. Now Idol has an app to go along with its dominant TV presence. American Idol Official features cast bios, news, and videos of the performances you might have missed on the show. It also features a large social media component, so discussing your favorite singers is a breeze via Facebook and Twitter.
The ESPN X Games app received a mega update recently. For starters, the app shifted its focus to the Winter X Games, so the menus received a chilly winter makeover. Feature-wise, X Games now has a built-in game called HypeMeter as well as ?Gamecast? functionality so users can follow the live results of X Games events. Just sit back and watch Shaun White shred the halfpipe and Roz Groenewoud?curise the slopes.
National Geographic's Weird But True, the app that brings users strange but true facts about everyday life, has updated with a bunch of new content. Its new design features 5 ?Fact Packs? filled with 625 unique ?weird but true? facts. You can also search across Fact Packs to find specific facts they want to share with their friends and family. In addition, you can rate each fact?s level of weirdness and compare with others.
Endless Alphabet helps kids learn their ABC?s alongside some basic grammar with fun, silly lessons and adorable monsters. Kids can learn phonics via interactive puzzles and the app constantly updates with new words. Currently, Endless Alphabet has dozens of words in its database and more are delivered on a regular basis. The app doesn?t score users, as it?s only focused on learning, not competition.
MyScript Calculator lets you solve serious math problems by simply drawing the problem out on your iPhone. Trying to find a square root divided by another number multiplied by another number? If you draw that problem on your iPhone, MyScript will solve it for you. MyScript Calculator solves basic operations like addition, subtraction and multiplication as well as more complex problems involving percentages, square roots, exponents, trigonometry, and logarithms.
Download the Appolicious Android app
Source: http://www.appolicious.com/tech/articles/13168-american-idol-official-leads-ios-apps-of-the-week
Sunday, January 27, 2013
zindabasa: Education & Reference 2020: The K-12 Implosion ...
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Source: http://exiguity-spiderweb.blogspot.com/2013/01/zindabasa-education-reference-2020-k-12.html
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Health News - Study eyes stem cell blood test to detect macular ...
A study led by researchers at the University of North Carolina School of Medicine is the foundation for a promising new blood test to detect the progression of macular degeneration to its more serious form, which can lead to blindness.
CHAPEL HILL, N.C. ? A study led by researchers at the University of North Carolina is the foundation for a promising new blood test to detect the progression of macular degeneration to its more serious form, which can lead to blindness.
Age-related macular degeneration (ARMD) is the most common cause of central vision loss in the western world. Those affected by?macular degeneration?find many daily activities such as driving, reading and watching TV increasingly difficult.
In the United States as many as 11 million Americans have some form of macular degeneration, including both early and later stages of the ?dry? and wet? forms. The eye condition deteriorates the macula, the central area of the retina, causing blind spots and blurred or distorted vision.
?People with macular degeneration start out with the dry type, which we can detect with a simple dilated eye exam,? says Dr. Sai H. Chavala, Director of the Laboratory for Retinal Rehabilitation and Assistant Professor of Ophthalmology and Cell Biology & Physiology at the UNC School of Medicine. He practices at the Kittner Eye Center at UNC Health Care in Chapel Hill and New Bern.
?But about 20 percent of patients at some time in their life will develop wet macular degeneration, which is characterized by blood vessels that grow under the surface of the retina. These abnormal vessels can leak blood and fluid, which causes irreversible damage to the cells of the retina leading to irreversible vision loss.? Since we don?t have a way to predict the precise timing of this event, we have no way of preventing it.? he adds.
Currently, no test is available to predict the conversion from dry to wet ARMD. But the new paper, published online Jan. 24, 2013, in the journal PLOS ONE, describes how it could be accomplished.
The ability to predict the conversion from dry to wet age-related macular degeneration is one of the most coveted achievements in vision science, according to Chavala. ?A clinical test that predicts impending conversion is the first step in developing treatments to prevent the switch to wet macular degeneration.?
In the study, the researchers used the Cell Search system, an FDA-approved technology for automated rare cell analysis (ARCA), which Chavala and colleagues applied to the identification and analysis of endothelial progenitor cells (EPCs). These cell types are rare compared to other blood cells.? EPCs are a stem cell subset that give rise to the endothelium found in the inner lining of blood vessels.? EPCs are liberated from the bone marrow and circulate in the blood in response to signals for new blood vessel growth.
Previous studies using fluorescence activated cell sorting (FACS), or flow cytometry, have demonstrated that EPCs are elevated in patients with wet macular degeneration compared to patients with the dry type.? However, FACS measurements are subject to substantial variability between observers, along with an element of subjectivity when measuring rare cell populations challenging its clinical use.
Chavala and colleagues thought that ARCA, a new technology capable of measuring rare cell populations reliably, was better suited as a diagnostic blood test. This technology is currently being used in clinical practice for cancer patients so the technology can be readily adopted for macular degeneration patients.
The study compared traditional FACS and ARCA in 23 subjects with age-related macular degeneration, both dry and wet. The samples were ?masked? so that no one involved in the sample assessments at the two labs where the analyses were done knew the type of macular degeneration the patients had.
?We found a promising trend favoring the ARCA technology in detecting a higher number of EPCs in the wet macular degeneration group compared to the dry. And that trend was not observed with traditional FACS,? Chavala said.? ?We were surprised that we needed to analyze relatively few patients to detect this trend.?
?Our ?proof of concept study? suggests that the ARCA technology could be a powerful tool for monitoring progression in macular degeneration.? Further study is required to validate this test for detecting and preventing the conversion from dry to wet macular degeneration.
?The next step is to do a prospective study in a greater number of subjects having the known criteria that puts them at higher risk of progressing from dry to wet macular degeneration,? Chavala said.?
Co-authors include lead author Emil Anthony T. Say, MD, at UNC Kittner Eye Center; Alex Melamud, MD, Retina Group of Washington, Washington, D.C.; Denise Ann Esserman, PhD, UNC Gillings School of Global Public Health; and Thomas J. Povsic, MD, PhD, Duke University Medical Center in Durham, N.C.
Support for the study came from the Adler Foundation, Hope for Vision, and Research to Prevent Blindness grants.
Disclosure Statement: Dr. Chavala has filed a patent surrounding this technology and is founder of Serrata, LLC, a company that plans to market diagnostic testing for ocular disease.
Media contact: Les Lang (919) 966-9366, [email?protected]
How Many People Have Been Killed by Guns Since Newtown?
The answer to the simple question in that headline is surprisingly hard to come by. So Slate and the Twitter feed @GunDeaths are collecting data for our crowdsourced interactive. This data is necessarily incomplete. But the more people who are paying attention, the better the data will be. You can help us draw a more complete picture of gun violence in America. If you know about a gun death in your community that isn?t represented here, please tweet @GunDeaths with a citation. (If you?re not on Twitter, you can email slatedata@gmail.com.) And if you?d like to use this data yourself for your own projects, it?s open. You can download it here.
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- Any Age Group
- Adult
- Teen
- Child
Matched Deaths: or more since Newtown
Show Methodology
Each victim under 13 years of age is designated "child"; from 13 to 17: "teen"; 18 and older: "adult."
The same icons used to represent male victims is also used to represent victims of unknown gender.
The same icons used to represent adult victims is also used to represent victims of unknown age group.
The yellow and blue backgrounds represent alternating days.
The information is collected by @gunDeaths from news reports about the deaths. The Slate interactives team and @gunDeaths continually manages and revises the data.
The data are not comprehensive because not all gun-related deaths are reported by the news media. For example, suicides often go unreported.
Source: http://feeds.slate.com/click.phdo?i=69ac6522a826ffe41ff70e9f2b4324be
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