Monday, June 4, 2012

led bulbs, led lamps - Led Lamps: An excellent power saving ...

led bulbs, led lamps - Led Lamps: An excellent power saving alternatives
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led bulbs, led lamps More Details about led bulbs, led lamps here.

Power consumption is the major issue all over the world. As a result, everybody is asked to follow green building norms. The best way to do so is by replacing conventional glowing bulbs with Led Bulbs at home and office. This will ease from high electricity bills. Based on LED technology, these led lamps and bulbs are excellent power saving alternatives to incandescent lights. This ground breaking lighting technology is easily accessible via internet. These lights display exceptional controllability through color mixing and never ending dimming control functions. These are highly recommended for offices and large shopping complexes. It is because this superior technology contributes in substantial power saving. It is a better choice for applications that need higher levels of illumination. Also, it is preferred for those places where lighting load is imperative. This has become very famous for astounding environmental performances. The demand for this cutting edge technology has gone high as appropriately fulfills the insistent need of the hour. At present a wide range of Led bulbs and Led lamps are offered in the market. The other choices available for purchase on the market as well as online are tubes, spotlight, ceiling lights, down light PAR lamp and many more. These are highly efficient and affordable products. All these products work using Green technology that creates suitable atmosphere for people in the buildings. Each of them is designed and manufactured as per accepted norms and standards such as CE, ERP, TUV, IEC, FCC, RoHS and INTERTEK. These global standards ensure that the product is reliable, durable and stable power saving alternatives. Usage of high quality standards guarantees maximum client satisfaction. Moreover, the entire range is checked thoroughly at each level on varied parameters to confirm superior quality and functionality. In a nutshell, these products incorporating latest technology provide the most satisfied series of products based on this innovative technology to people worldwide. These Led Lamps and bulbs have been very successful in replacing CFLs which were considered important power saving lights earlier. And now it is this technology that aims to make our planet green and happy. Consistent effort is made by technocrats to improve the quality and offer more efficient Led solutions to people. The technology is further exploited for providing functional lighting. To know more about the product, surf the internet. It is believed that the technology will assist us in resolving many power related issues without much of difficulty. So order your product now online and benefit from its remarkable features.

Want to find out more about Led Bulbs, then visit site on how to choose the best LED Lamps for your needs.

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In depth: Unified communications still fragmented | Fire and Security ...

Unified communications (UC) technology has garnered a fair amount of attention, much of it due to vendors touting their UC offerings as the answer to problems workers have keeping in touch with colleagues, business partners and customers in a highly frenetic, increasingly mobile business world.

While the technology is delivering benefits to the relatively few organizations that have adopted it, experts say UC is still evolving and vendors need to do more to integrate their various products.

Exactly what UC is depends on who?s providing the definition, but in general it includes real-time communication capabilities such as telephony (including IP), video conferencing, instant messaging (IM), telepresence and data sharing, along with non-real-time services such as voicemail, email, unified messaging and fax.

[ Stay connected with the latest on networks and the NBN in Computerworld's Networking newsletter ]

UC often involves multiple product components that together provide a unified user interface and experience across devices and media types. Among other capabilities, it allows a user to be reachable via the same telephone number over a variety of devices, and to receive messages on the medium of his or her choosing.

The idea behind the technology is to optimize communication and collaboration ? enabling workers to more easily reach and be reached by others, and therefore be more efficient and productive.

Best practices for UC adoption

When implementing a unified communications system, hire consultants or integrators with expertise in the new system as well as legacy telecom systems in place. Knowledge about both will help the installation and transition go more smoothly and avoid integration and compatibility problems.
Tap into resources such as other organizations that have deployed UC and overcome challenges your organization might face, such as cultural change or integration with legacy communications systems. Ask vendors for customer references.
Make sure the vendor, systems integrator or consultant has the resources to set up and test the system in a lab setting before rolling it out within the organization. All functionality should be tested to make sure everything works as planned given the company?s network infrastructure, phone sets, mobile devices, and so on.
Provide detailed training to users on UC features and capabilities, particularly to those who have never used the technology before. Without training and an explanation of the benefits of features, people are less likely to take advantage of them.
If the company has a mix of vendor UC systems (for example, as a result of merger and acquisition activity), ensure that applications can be developed and deployed on multivendor infrastructures.
For very large organizations (e.g., 10,000 users in multinational locations), consider a phased rollout of UC. Implementing the new services in small increments to a limited number of users enables the company to understand how each application works and what support structure it requires before a full-scale rollout.

But despite the promise, uptake of the technology has been somewhat sluggish, according to industry observers.

?We have not seen significant growth in the number of companies doing something with UC,? says Robin Gareiss, executive vice president and senior founding partner of Nemertes Research Group, a research and advisory firm in Mokena, Ill. Based on surveys the firm has conducted, only 4.4% of companies have fully deployed UC.

Two key issues are slowing adoption, Gareiss says. One is that companies are having a hard time establishing a hard-dollar business case for UC, and the other is that vendors are not making integration of various UC components easy.

Determining how much UC will cost can be tricky because of the various components involved. ?Much of this depends on how you?re defining UC,? Gareiss says. ?Which apps are included? Are they fully integrated to both tethered and wireless devices? The biggest unplanned expenses are integration costs, training/marketing internally to users and management tools.?

Fortunately, UC can be deployed in increments, rather than require a major infrastructure upheaval, says Don Van Doren, principal at UniComm Consulting LLC in Loomis, Calif. Companies can purchase the UC capabilities and licenses as needed. ?This means that savings from early improvements can be used to help fund subsequent application implementations,? he says.

Despite the slow growth of the market overall, UC holds promise for organizations, Gareiss says.

In fact, some believe that the boom in mobile communications will help spur demand for UC as a way of tying it all together, and to help enable the promise of anywhere, anytime connectivity across multiple types and brands of devices. Analyst firm Info-Tech Research Group uses mobility as one key factor in its recently released UC scorecard.

UC successes

Companies that have deployed UC are seeing results. Underwriters Laboratories (UL) of Northbrook, Ill., a global independent product-safety science company, two years ago implemented a UC platform that includes components from Microsoft, Hewlett-Packard and Avaya.

The company wanted to improve communications and collaboration throughout the organization and at the same time upgrade an aging communications and networking infrastructure, says Tom Boxrud, IT director, global operations at UL.

As part of the upgrade, the company deployed Microsoft?s Office Communications Server (OCS) 2007 R2 unified communications platform, which integrates instant messaging, audio, video, Web conferencing and telepresence into Microsoft Office. It also deployed a voice over IP (VoIP) telephony system from Avaya and network-infrastructure components including switches from HP.

?We had outgrown our existing technology, but additionally UL was in a period of transformation, and one goal was to improve communications and collaboration? with customers, Boxrud says.

We have not seen significant growth in the number of companies doing something with UC. Robin Gareiss, executive vice president, Nemertes Research Group

In addition, the company wanted to reduce travel costs, shorten project cycles and be more agile in the marketplace. ?We saw unified communications as a key tool that could deliver that,? Boxrud says. The company is in the process of moving to Microsoft Lync, the vendor?s latest UC offering.

As a result of using UC and VoIP, UL expects to reduce its telecommunications costs by as much as 50%, Boxrud says. Much of that savings comes from reduced long-distance calling costs among its global offices. Furthermore, UL has cut operating costs by 30%, consolidating nearly 40 email servers worldwide to just one cloud-based email system.

Collaboration among its facilities in North America, Europe and Asia is much easier and less costly since the adoption of UC, Boxrud says. ?When we test products, we might have someone [in Asia] with knowledge about a product UL may be testing that someone in North America needs access to,? he says. ?Instead of sending that person there we can do point-to-point demos or [Web] conferencing with the click of a button.?

But the adoption of unified communications has come with some challenges. For one thing, it?s been something of a cultural shift for many people in the organization, who had never used the types of advanced features provided by UC.

?Being that we have an older culture here, the key to the overall implementation [of UC] is having a good [internal] marketing, communications and training campaign ? which we did through our Internet site and self-service tools ? so people could see? how to use UC features, Boxrud says.

The company rolled out features gradually rather than all at once to minimize struggle, Boxrud says. ?We did a lot of feedback surveys about how people were feeling about the tools,? he says. ?Some people had never been exposed to the video capabilities before.?

As for financial payback, Boxrud says UL expects a return on investment on its UC technology and other network upgrades within about three years. ?That?s pretty much on par with what we anticipated,? he says.

UC as part of a broader revamp

Another UC user, The Agency Group, a London-based booking agency that represents more than 1,500 music artists worldwide, began deploying Avaya Inc.?s Avaya IP Office 7.0 in late 2010 as part of a telecommunications overhaul to improve communications among its worldwide offices.

Part of the reason for the move was that the firm wanted to upgrade its communications infrastructure from an older Nortel system that wasn?t IP-enabled and that the business had outgrown, according to Howie Gold, CIO at The Agency Group.

?We needed more trunking capabilities and more overall features, such as video conferencing and support for iPhone and Android mobile applications,? Gold says. But another key reason for adopting unified communications was to achieve the firm?s goal of ensuring always-on, real-time service for clients, regardless of their location.

The Agency Group also wanted to increase productivity among its employees, improve collaboration, save costs and reduce travel ? and it has achieved those objectives with the new system, Gold says. Perhaps most important, UC enables the firm ? which also has offices in New York, Los Angeles, Toronto, Sweden and Nashville and has a large number of highly mobile employees ? to have a cohesiveness that it lacked before.

?Our chairman?s main focus for IT was to unify the company, to enhance our level of communications and to get people from different offices to share information,? Gold says.

Other immediate benefits for users included increased convenience and greater efficiency with managing communications. The system allows people to make calls to anywhere within the organization by dialing four digits. That eliminates the need for cumbersome international dialing, Gold says.

?We have a lot of communications between agents in the U.K. and Canada [for example], and they now have the ability to just pick up the phone and dial a four-digit extension and reach someone 4,000 miles away without any concern that it?s a long-distance call,? Gold says.

Adopting or planning UC? Is your organization using, or planning to implement or upgrade, UC and collaboration solutions? Currently using/running ? 52% Planning to implement within 1 year ? 32% Source: IDG Enterprise survey, March 2012, 1,105 respondents

Even in this age of electronic communication the agency relies heavily on phone connections, Gold says. ?You can do so much with email, but our business is a relationship business that requires personal communications,? he says. ?It?s better if people can get a feel for a person?s sense of humor or their excitement about a band.?

The system has an application that allows users to send instant messages and see a colleague?s presence, among other functions, from a Web-based portal. This allows mobile agents to remain transparently available to clients, regardless of their location.

UC has also allowed the firm to save money through reduced long-distance calling and the avoidance of hotel calling charges, Gold says. While he wouldn?t quantify total savings, Gold says executives and agents can avoid calling costs of as much as $3,000 for a single overseas trip.

?There are so many different levels of savings that if you [consider that] and factor in the enhanced level of communications that goes with it, it?s hard to say what the total value of the technology is, but it is exceptional,? Gold says.

Without concerns about calling costs, people are more inclined to make calls they need to make to do their jobs. ?One of the senior VPs told me that [in the past] when he would travel he would make a call to the office and then bounce around to different people in the office so he wouldn?t have to make separate calls,? Gold says. ?Now he doesn?t have to get it all done in one call to save toll charges. It raises the level of communications because in the past people might have tried to avoid making calls.?

Still evolving

Some IT executives see UC technology as a work in progress, with improvements still needed.

?There is a need for more well-defined standards and protocols for communication between technologies, thus enabling simple integration,? says Jim Spicer, executive vice president/group executive and CIO, Wells Fargo Corporate Technology and Data, at financial services firm Wells Fargo & Co. in San Francisco.

For now, he predicts, this integration improvement will happen in only ?a subset? of UC areas, because most vendors see competitive advantage in having proprietary formats. ?We would hope that as the capabilities evolve [we] might see this improve.?

Within UC, ?there is a need for more well-defined standards and protocols for communication between technologies, thus enabling simple integration,? says Jim Spicer, CIO of Wells Fargo Corporate Technology and Data.

In addition, Spicer would like to see UC products better support the data archiving and discovery needs of companies, which he says are growing and currently require much custom integration and effort. Many companies need this archiving capability for regulatory compliance purposes. ?Convergence across some of the vendor products in the market to make this simpler and less costly would be valuable,? he says.

Wells Fargo implemented a UC system ? which Spicer declined to identify ? in part to increase productivity and collaboration among staff and to meet demand for instant, real-time communication.

The firm has seen benefits, such as the ability to connect teams across diverse geographical areas in a more real-time way, and in the future expects to see gains including reduced need for travel, the ability for users to see each other face-to-face in real time for interactive discussions, and more effective team meetings conducted remotely.

Providing a compelling UC business case can be a challenge when trying to justify the deployment across a large organization such as Wells Fargo, Spicer says. ?Obviously, not everyone within the bank needs UC to get their job done well,? he says. ?As the benefits continue to climb with new and more streamlined capabilities and the costs continue to fall with better integrated products and higher capacity infrastructure, the ROI will become easier to support.?

UC will continue to evolve, experts say. Gareiss expects to see more integration with mobile devices, or the ability to access a consistent set of UC features from any device. She also predicts more video on different types of devices, and more integration of the various video systems (telepresence, room-based, desktop, and mobile).

And, as with so many areas of computing today, the cloud is having an impact on UC.

?Cloud-based UC is gaining interest, but not huge adoption yet among all sizes of companies,? Gareiss says. ?For now, we see small and midsize companies, those with fewer than about 1,000 endpoints, making the strongest business case for cloud or hosted UC services.?

UC ?is not an IT project that is truly ever ?completed,?? Gareiss says. ?It?s an evolution, and IT staffs will always add new communications, collaboration, enterprise and mobile applications to an overall UC framework.?

Bob Violino is a freelance writer in Massapequa Park, N.Y. You can reach him at bviolino@optonline.net.

Read more about networking in Computerworld?s Networking Topic Center.

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Saturday, June 2, 2012

Can SpaceX build the pick-up trucks of space?

"LIKE the smell of a brand-new car." So said US astronaut Don Pettit as he entered the Dragon space freighter after it docked with the International Space Station last week (see "Spectacular images show moment SpaceX Dragon docked").

Pettit's words speak to the slickness of the SpaceX craft - which was, after all, created by a man who has form in making cars. Elon Musk's Tesla Motors has done much to make electric cars desirable: its head-turning Roadster revolutionised ideas about what an emissions-free vehicle might achieve.

But SpaceX cannot just build the Roadsters of the space business. Reliable workhorses are what's needed, not ritzy performance vehicles. The vast majority of the $60-million cost of a SpaceX launch comes from its Falcon rocket. This currently burns up on re-entry, but the company aims to make it fully reusable. The shuttle fell short of this goal, but SpaceX thinks it can succeed where NASA failed.

Can it? Tesla Motors is now building on the Roadster's technology to roll out a family sedan and an SUV. If SpaceX proves similarly adroit, astronauts can look forward to more new car smells to come.

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Seeking Professional Auto Repairs For Car Collisions - UNITED CMS

Seeking Professional Auto Repairs For Car Collisions
Car collisions are one of the many reasons why people in California seek professional auto repairs. Although many people believe that having cars repaired at auto repair shops can cost a lot, they are willing to pay these car repair services to bring back the original beauty and value of their cars.

Car collisions not only damage your cars exteriors, they can also cause your engine and car systems to malfunction. That is why its important to have your car checked for any damages as soon as possible if it recently got involved in a car accident.

There are many things to consider when repairing your damaged car. To bring back your cars original appearance, you have to consider the original paint color, shape, contour, electrical and mechanical functions, and its safety features. That is why you need to seek professional services to help you get through the process of repairing your car. Here are several guidelines you need for your car repairs.

Dealing with insurance companies

Letting your insurance company know about your recent car mishap is the first thing you need to do. Insurance companies will help you in recover from the car accident. They will subsidize your car repair costs and get you through the process of recuperating physically and financially. Your insurance company will also recommend a list of Beverly Hills auto body repair shops that can provide estimations for your insurance claims.

Find the right auto repair shop

The next step is to find a reputable auto repair West Hollywood shop to help you estimate the cost of your car repairs and provide you repairing services. If youre dealing with a recommended shop from your insurance agent, theres a chance that you might get discounts for your car repairs. Make sure that you choose a reputable and a professional auto repair shop to assure that your car body repairs will resemble its original look.

Reducing costs

Reducing the cost of your car repairs is important. You can reduce the cost of your car repairs by asking your auto repair West Hollywood shop to use aftermarket components. You can talk to your mechanics and let them know that you are on a tight budget. Moreover, you can look around for different auto repair shops that can offer affordable rates.

Visit www.eurodesignauto.com for more details.

Tags: Auto, Collisions, Professional, Repairs, Seeking

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Friday, June 1, 2012

Mitt's Massachusetts (The Note)

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House OKs veterans' health care, disability bill (cbsnews)

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NYUCD receives grant to identify biomarkers for the progression of periodontal disease

NYUCD receives grant to identify biomarkers for the progression of periodontal disease [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

New York University College of Dentistry has been selected as one of five institutions that are sharing a $20.7 million grant from the National Institute of Dental and Craniofacial Research (NIH) to the Forsyth Institute to find new ways to diagnose and fight periodontal disease. As the recipient of a $1.8 million subcontract, the NYU College of Dentistry will screen research subjects and collect biological samples that will contribute to the overall project, "Biomarkers of Periodontal Disease Progression."

This major, five-year project, involving 500 subjects across all sites, explores periodontal disease from the microbiological, genetic, and immunological perspectives. The goals are to expand the use of biomarkers to understand why people develop periodontal disease, under which circumstances the disease is most likely to progress, and how periodontal treatment impacts patients' biomarkers.

To varying degrees, periodontal disease affects 40 percent of adults in the United States and can lead to loss of bone that supports the teeth. NYU will focus on identifying biomarkers among 75 subjects with periodontal disease compared with 25 control subjects.

In December 2011, NYU began to collect clinical indicators and biological samples such as saliva, plaque, and gingival crevicular fluid from research subjects. It will send these samples to the Forsyth Institute for analysis to identify biomarkers. The Forsyth Institute is an independent research organization that focuses on oral health.

"Biomarkers are factors in people's blood, dental plaque, saliva, or tissue that might indicate that they are more susceptible than others to developing periodontal disease," says Dr. Patricia Corby, principal investigator on the NYU College of Dentistry grant and assistant professor of periodontology and implant dentistry and associate director of the NYU Bluestone Center for Clinical Research. "By identifying these factors, we will be able to design more specific treatments for this condition; thus we're changing the paradigm of how we diagnose and treat periodontal disease."

A traditional biomarker for periodontal disease is bleeding on probing. Other biomarkers include a high degree of disease-associated bacterial colonization affecting the tissues that surround and support the teeth or the presence of cytokinestypes of proteins that are secreted by numerous cells in the body, which are associated with inflammation. Biomarkers may indicate the presence or absence of periodontal pathogens, gingival and periodontal inflammation, an inflammatory-immune response to certain pathogens, or tissue destruction.

Although these biomarkers can be associated with periodontal disease, they also can be associated with other systemic diseases. To isolate biomarkers for periodontal disease, researchers will exclude any patients with other systemic diseases such as heart disease or diabetes. Because so many periodontal patients do have comorbidities, the researchers expect to screen 10 subjects for each one who fits the criteria.

In addition to looking for biomarkers through this study, researchers are exploring a novel approach to treat periodontal disease. According to Dr. Corby, periodontists generally treat the entire mouth with scaling and root planingunder the assumption that the entire mouth is affected or as a preventive treatment approach. Research at the Forsyth Institute has shown that progression of the disease is site-specific as well as episodic. Patients may do well with a more conservative approach to treatment and steady monitoring to determine whether and where the disease is progressing, says Dr. Corby. Patients in the study will return every two months for monitoring of specific sites and to see whether changes have occurred. In places where the disease is advancing, researchers will treat only the parts of the mouth that are progressing toward disease.

"We want to look at people who respond to this therapy and see how their biomarkers change due to the therapy that we're proposing," says Dr. Corby, noting that the presence of certain biomarker microbes might make some sites in the mouth progress more quickly than others. "If the study succeeds (and this is a preliminary trial), it might change the way the profession treats periodontal disease."

A theory underpinning the study is that periodontal disease is not just a chronic infection, as was once thought, but is related as much, if not more, to inflammation and other immune-system functions. Understanding the biomarkers for inflammation that are associated with periodontal disease will help determine how to treat people.

In addition to Dr. Corby, co-investigators from the NYU College of Dentistry include Dr. Robert Schoor, clinical associate professor of periodontology and implant dentistry and director of the Advanced Education Program in Periodontics; Ms. Rosemary Hays, clinical associate professor of dental hygiene and assistant academic director of the dental hygiene program; Ms. Cynthia J. Howard, clinical assistant professor of dental hygiene and junior research scientist at the NYU Bluestone Center for Clinical Research; and Ms. Judith Kreismann, clinical associate professor of dental hygiene.

The overall project is led by Dr. Richard Teles, a senior member of the staff at the Forsyth Institute and director of the Center for Clinical and Translational Research at Forsyth. Dr. Teles hopes ultimately to develop diagnostic tests to help identify subjects and sites in the mouth that are most susceptible to periodontal disease progression.

###

About New York University College of Dentistry

Founded in 1865, New York University College of Dentistry (NYUCD) is the third oldest and the largest dental school in the US, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


NYUCD receives grant to identify biomarkers for the progression of periodontal disease [ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Christopher James
christopher.james@nyu.edu
212-998-6876
New York University

New York University College of Dentistry has been selected as one of five institutions that are sharing a $20.7 million grant from the National Institute of Dental and Craniofacial Research (NIH) to the Forsyth Institute to find new ways to diagnose and fight periodontal disease. As the recipient of a $1.8 million subcontract, the NYU College of Dentistry will screen research subjects and collect biological samples that will contribute to the overall project, "Biomarkers of Periodontal Disease Progression."

This major, five-year project, involving 500 subjects across all sites, explores periodontal disease from the microbiological, genetic, and immunological perspectives. The goals are to expand the use of biomarkers to understand why people develop periodontal disease, under which circumstances the disease is most likely to progress, and how periodontal treatment impacts patients' biomarkers.

To varying degrees, periodontal disease affects 40 percent of adults in the United States and can lead to loss of bone that supports the teeth. NYU will focus on identifying biomarkers among 75 subjects with periodontal disease compared with 25 control subjects.

In December 2011, NYU began to collect clinical indicators and biological samples such as saliva, plaque, and gingival crevicular fluid from research subjects. It will send these samples to the Forsyth Institute for analysis to identify biomarkers. The Forsyth Institute is an independent research organization that focuses on oral health.

"Biomarkers are factors in people's blood, dental plaque, saliva, or tissue that might indicate that they are more susceptible than others to developing periodontal disease," says Dr. Patricia Corby, principal investigator on the NYU College of Dentistry grant and assistant professor of periodontology and implant dentistry and associate director of the NYU Bluestone Center for Clinical Research. "By identifying these factors, we will be able to design more specific treatments for this condition; thus we're changing the paradigm of how we diagnose and treat periodontal disease."

A traditional biomarker for periodontal disease is bleeding on probing. Other biomarkers include a high degree of disease-associated bacterial colonization affecting the tissues that surround and support the teeth or the presence of cytokinestypes of proteins that are secreted by numerous cells in the body, which are associated with inflammation. Biomarkers may indicate the presence or absence of periodontal pathogens, gingival and periodontal inflammation, an inflammatory-immune response to certain pathogens, or tissue destruction.

Although these biomarkers can be associated with periodontal disease, they also can be associated with other systemic diseases. To isolate biomarkers for periodontal disease, researchers will exclude any patients with other systemic diseases such as heart disease or diabetes. Because so many periodontal patients do have comorbidities, the researchers expect to screen 10 subjects for each one who fits the criteria.

In addition to looking for biomarkers through this study, researchers are exploring a novel approach to treat periodontal disease. According to Dr. Corby, periodontists generally treat the entire mouth with scaling and root planingunder the assumption that the entire mouth is affected or as a preventive treatment approach. Research at the Forsyth Institute has shown that progression of the disease is site-specific as well as episodic. Patients may do well with a more conservative approach to treatment and steady monitoring to determine whether and where the disease is progressing, says Dr. Corby. Patients in the study will return every two months for monitoring of specific sites and to see whether changes have occurred. In places where the disease is advancing, researchers will treat only the parts of the mouth that are progressing toward disease.

"We want to look at people who respond to this therapy and see how their biomarkers change due to the therapy that we're proposing," says Dr. Corby, noting that the presence of certain biomarker microbes might make some sites in the mouth progress more quickly than others. "If the study succeeds (and this is a preliminary trial), it might change the way the profession treats periodontal disease."

A theory underpinning the study is that periodontal disease is not just a chronic infection, as was once thought, but is related as much, if not more, to inflammation and other immune-system functions. Understanding the biomarkers for inflammation that are associated with periodontal disease will help determine how to treat people.

In addition to Dr. Corby, co-investigators from the NYU College of Dentistry include Dr. Robert Schoor, clinical associate professor of periodontology and implant dentistry and director of the Advanced Education Program in Periodontics; Ms. Rosemary Hays, clinical associate professor of dental hygiene and assistant academic director of the dental hygiene program; Ms. Cynthia J. Howard, clinical assistant professor of dental hygiene and junior research scientist at the NYU Bluestone Center for Clinical Research; and Ms. Judith Kreismann, clinical associate professor of dental hygiene.

The overall project is led by Dr. Richard Teles, a senior member of the staff at the Forsyth Institute and director of the Center for Clinical and Translational Research at Forsyth. Dr. Teles hopes ultimately to develop diagnostic tests to help identify subjects and sites in the mouth that are most susceptible to periodontal disease progression.

###

About New York University College of Dentistry

Founded in 1865, New York University College of Dentistry (NYUCD) is the third oldest and the largest dental school in the US, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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